The US healthcare sector relies on digital tools to manage care, data, and patient interactions. From EHR systems to telemedicine and analytics, software now supports most clinical and operational workflows.
As demand grows, many organizations turn to the top healthcare software development companies in USA to build reliable and compliant solutions.
This guide highlights companies that develop both enterprise platforms and custom healthcare software. It offers a clear starting point for comparing providers and understanding the current market.
Epic Systems is a privately held healthcare software company based in Verona, Wisconsin. Founded in 1979, it develops large-scale health information systems, with a strong focus on electronic health records (EHR). Its software is used by hospitals, clinics, and healthcare networks across the United States. Epic is often listed among the top healthcare software development companies in USA due to its broad adoption and long presence in health IT.
The company’s platform connects clinical, administrative, and financial workflows in one system. Epic software supports patient records, scheduling, billing, analytics, and patient engagement tools such as MyChart. The platform is designed to centralize medical data and make it accessible across departments and care settings. This helps healthcare organizations manage operations and coordinate care more effectively.
Oracle Corporation is a global technology company that provides cloud infrastructure, databases, and enterprise software, including solutions for the healthcare sector. Its healthcare division, Oracle Health, was formed after the company acquired Cerner in 2022, expanding its role in health information technology. This positioned Oracle among the top healthcare software development companies in the US, with a focus on large-scale systems used by hospitals and healthcare networks.
Oracle Health builds platforms that support clinical, financial, and day-to-day operations in healthcare. Its solutions include electronic health records, data analytics tools, and cloud systems for managing patient information. These tools bring data into one place, connect different systems, and help care teams make more informed decisions across settings.
Athenahealth is a US-based healthcare technology company founded in 1997 and headquartered in Boston, Massachusetts. It provides cloud-based software and services for medical practices and healthcare organizations. The company focuses on improving clinical and administrative workflows through connected digital tools. It is often included among the best healthcare software development companies in USA due to its strong presence in ambulatory care and cloud-based health IT.
Athenahealth develops platforms that combine electronic health records, revenue cycle management, and patient engagement tools in one system. Its main product, athenaOne, integrates clinical, financial, and operational functions. The platform supports data exchange across healthcare networks and helps streamline documentation, billing, and patient communication.
MEDITECH (Medical Information Technology, Inc.) is a US-based healthcare software company founded in 1969 and headquartered in Massachusetts. It develops health information systems, with a primary focus on electronic health records (EHR) used by hospitals and healthcare organizations. The company has a long presence in the health IT market and is often included among the top healthcare software development companies in the US due to its established EHR platforms and broad use across care settings.
MEDITECH’s core platform, Expanse, is a web-based and mobile EHR designed to support clinical workflows, data management, and care coordination. Its software helps healthcare providers manage patient records, documentation, billing, and operational processes in one system. The platform also supports interoperability and cloud-based access, allowing teams to work with patient data across departments and locations.
GE HealthCare is an American healthcare technology company headquartered in Chicago, Illinois. It operates as an independent company since 2023 and focuses on medical technologies, diagnostics, and digital healthcare solutions. Its products and software are used by hospitals and healthcare systems across the United States and globally. The company is often associated with custom healthcare software development in USA, especially through its digital platforms and data-driven tools.
GE HealthCare develops software that supports clinical workflows, imaging, and patient data management. Its platforms include tools for enterprise imaging, analytics, and decision support. The company also builds systems that connect devices, collect healthcare data, and provide real-time insights. These solutions help healthcare organizations manage operations and support diagnosis, treatment, and patient monitoring.
Cognizant is a US-based multinational technology company headquartered in Teaneck, New Jersey. Founded in 1994, it provides IT services, consulting, and outsourcing across industries, including healthcare. The company works with healthcare providers, payers, and life sciences organizations to support digital transformation and system modernization. It is often included in discussions around custom healthcare software development in USA due to its large-scale engineering and consulting capabilities.
Cognizant develops and implements healthcare solutions that combine software platforms, data, and business processes. Its offerings include AI-driven tools, data analytics, and systems that connect payers and providers. The company also works on workflow automation, claims processing, and patient experience solutions, helping healthcare organizations manage operations and adapt to changing requirements.
Veradigm is a US-based healthcare technology company headquartered in Chicago, Illinois. Formerly known as Allscripts, the company focuses on data-driven healthcare solutions that connect providers, payers, and life sciences organizations. Its platforms combine data, analytics, and clinical tools to support decision-making and care delivery. Veradigm is often associated with cloud based EHR development, especially through its integrated health IT systems and provider-focused solutions.
Veradigm builds EHR systems and tools for clinical, financial, and daily operations. Its platforms are made for ambulatory practices. They include features for workflow automation, reporting, and patient data management. The company also offers tools for billing, patient engagement, and data exchange. These help healthcare teams run operations better and coordinate care.
eClinicalWorks is a US-based healthcare technology company that develops electronic health record (EHR) and practice management software. Founded in 1999, it provides cloud-based solutions used by medical practices, clinics, and healthcare organizations across the country. Its platforms support clinical documentation, scheduling, billing, and patient data management. The company is often mentioned in discussions around healthcare software development cost USA, as its systems are widely used by ambulatory care providers and smaller practices.
eClinicalWorks offers one platform that brings together EHR, telehealth, patient engagement, and billing tools. It supports the full patient journey, from intake and notes to billing and follow-up. The system also automates routine tasks and helps teams stay organized. These tools reduce admin work and help clinics run more efficiently.
ScienceSoft is a US-headquartered IT consulting and software development company founded in 1989 and based in McKinney, Texas. It provides services across multiple industries, including healthcare, with a focus on custom software engineering and digital transformation. The company has worked in healthcare IT since 2005, helping organizations design and modernize compliant medical solutions.
ScienceSoft builds end-to-end healthcare software. It covers patient engagement, data management, and connected care. The company creates telehealth platforms, mobile apps, and IoT tools for monitoring and data sharing. It is known for remote patient monitoring software development. Its systems connect devices, collect patient data, and support care outside clinics.
Mindbowser is a US-based software company that builds digital health solutions for startups, providers, and healthcare teams. Founded in 2015, it works on custom healthcare software, AI tools, and system integration. The company builds compliant systems that support data exchange, patient engagement, and daily clinical work. It is often linked to HL7 integration healthcare software, especially when projects require connecting multiple systems.
Mindbowser develops solutions that enable interoperability between EHRs, medical devices, and third-party applications using standards like HL7 and FHIR. Its services include custom interface development, integration with billing and clinical systems, and tools for analyzing healthcare data. The company also builds platforms that support real-time data exchange and workflow automation, helping healthcare organizations improve coordination and reduce manual processes.
The healthcare IT companies in USA play a key role in shaping how care is delivered, managed, and improved. From large enterprise platforms to custom-built solutions, these companies support healthcare providers with tools for data management, patient engagement, and operational efficiency. Each company brings a different focus, whether it is system scale, integration, or specialized development.
This list gives a practical overview of the current landscape and helps narrow down potential partners. Choosing the right provider depends on your goals, technical requirements, and the level of customization you need.
If you want to feature your healthcare software development company on this list, email us or submit a form in the Top Choices section. After a thorough assessment, we’ll decide whether it’s a valuable addition.