Choosing between telemedicine app development firms is harder than it looks, because almost every software shop now lists “telehealth” on its services page. The firms worth shortlisting can show the work: video visit platforms in production, e-prescribing wired into Surescripts, EHR connections built on HL7 and FHIR, remote patient monitoring that feeds device readings back to clinicians, and architecture designed around HIPAA safeguards from the first sprint.
This list covers ten companies that publish telehealth case studies on their own sites, from healthcare-only studios in the US to large engineering firms in Europe. We looked at what each one has actually shipped, who it builds for, and which buyers it fits best. If your project leans more toward clinical AI than virtual visits, our guide to AI for healthcare implementation companies covers that side of the market, and our list of custom software development companies covers general engineering partners.
One note before the list: there is no such thing as a “HIPAA certification” for a software vendor. What you want is a partner that signs a Business Associate Agreement, builds on HIPAA-eligible cloud services, and can show audit logging, access controls and encryption in the systems it has delivered. Treat any firm that claims to be “HIPAA certified” with caution.
| Company | Headquarters | Best For | Core Services |
| Topflight | Irvine, US | Funded digital health startups shipping an MVP | Telehealth apps, e-prescribing, RPM, FHIR and HL7 integration |
| Mindbowser | Jersey City, US | Teams that need deep Epic and Cerner integration | Telehealth apps, SMART on FHIR, RPM, care management platforms |
| ScienceSoft | McKinney, US | Providers wanting a regulated, ISO 13485 vendor | Telehealth portals, RPM, EHR integration, consulting |
| Taction Software | US offices and Noida, India | Health systems launching enterprise virtual care | Video visits, Surescripts e-prescribing, Epic integration, billing |
| Arkenea | United States | Practices that want a healthcare-only US vendor | Telehealth platforms, patient apps, custom EHR |
| Riseapps | Lake Mary, US and Tallinn, Estonia | Clinics launching branded virtual care | Telemedicine apps, patient portals, athenahealth and eClinicalWorks apps |
| Orangesoft | US and Poland | FDA-regulated remote care programs | Telemedicine apps, medical device software, IoMT |
| Thinkitive | Dover and Edison, US | Provider groups needing EHR-heavy builds | Telehealth, EHR integration, e-prescription, SMART on FHIR |
| Itransition | Decatur, US and London, UK | Enterprises needing scale and Microsoft Cloud for Healthcare | Telemedicine platforms, RPM, telemedicine-ready EHR |
| Innowise | Warsaw, Poland | Telehealth vendors needing native iOS and Android apps | Native telemedicine apps, video, EHR integration |
Healthcare specialists come first, followed by larger engineering firms with dedicated telehealth practices.
Topflight is an Irvine, California firm that builds HIPAA-compliant healthcare apps and AI tools for clinicians, operators and health tech founders. Its telemedicine practice covers video visits, scheduling, messaging and e-prescribing with refill requests, plus remote patient monitoring that pulls device readings into the chart with clinician-set alert thresholds. Integration work uses FHIR, HL7 and SMART on FHIR, and the company also builds specialty products for teledermatology, teleneurology, telepsychiatry and telecardiology.
The proof on its site is specific. For AlgoRX, a prescription e-commerce platform, Topflight built multi-pharmacy routing and a patient portal on NextJS, Supabase and DoseSpot, and the company says the MVP shipped on time and the client kept it on for ongoing work. It also lists a symptom tracking platform for a San Francisco telehealth company, a mobile telehealth app for iOS and Android, and Geneium, a teledermatology app for ARA Genomics that exports DNA-based skincare reports to dermatologists. Stanford Medicine and Merck appear among its named clients for remote monitoring work in clinical trials.
One useful detail for budgeting: Topflight publishes planning ranges for telemedicine app development on its site, though the figures differ between sections of the page, so confirm current pricing directly.
Best for: funded digital health startups that need a product partner to take a telehealth MVP from scope to launch, especially products that involve prescribing or specialty care.
Mindbowser lists its US address in Jersey City, New Jersey, and describes a team of 200+ HIPAA- and FHIR-trained professionals with more than 250 completed projects. Its telemedicine app development service covers real-time video consultations, EHR integration, scheduling, secure messaging, prescription management and billing integration, with specialty builds for mental health, pediatrics, urgent care, nursing, physical therapy and neurology.
Integration depth is the main reason to shortlist it. The company lists Epic and Oracle Cerner as partners, publishes an “Epic SMART on FHIR Integration for Labor & Delivery” case study, and names athenahealth, eClinicalWorks and NextGen Healthcare among the EHRs it connects to. Its telehealth case studies include a secure telemedicine platform delivered in 21 days: two senior developers added a native iOS app, teleconsent inside the WebRTC and TokBox video session, HIPAA-compliant in-app messaging, and analytics for a fast-growing platform that clinicians use through personalized room links. Other published work includes an APCM, RPM and behavioral health platform for care management. doxy.me and Nuvance Health appear among the client logos on its telemedicine page.
On security, Mindbowser says it is SOC 2 Type II audited and describes its delivery as HIPAA-ready, with PHI safeguards built into access, environments and release workflows.
Best for: provider organizations and health tech companies whose telehealth product lives or dies on clean data exchange with Epic, Cerner or other major EHRs.
ScienceSoft is headquartered in McKinney, Texas, and says it has worked in healthcare IT since 2005. It holds ISO 13485, ISO 27001 and ISO 9001 certifications, which matters if your telemedicine product edges toward regulated medical device territory. The service splits into consulting (needs analysis, architecture, integration planning, cost and ROI estimates, and a regulatory compliance plan) and full development, with the company stating that an MVP covering high-priority features typically takes four to eight months.
Its telemedicine case study library is one of the deepest on this list. Published projects include a HIPAA-compliant telehealth app the company says improved outcomes by 4%, an EHR-integrated telehealth portal attracting about 10 new patients a day, remote patient monitoring software using Android sensors, a primary care telehealth app designed in four weeks, an iOS telemedicine MVP for a mental health startup delivered in four months, and a microservices-based telehealth solution delivered in nine months. It also lists a telehealth app audit and refactoring project that led to a HIPAA-compliant MVP launch, which is useful if you are rescuing an existing build.
Technically, its architecture covers video consultations, FHIR-based EHR integration, NCPDP SCRIPT for prescription data exchange, and connected medical devices for remote monitoring.
Best for: hospitals, clinics and medtech companies that want an established, quality-certified vendor and a consulting phase before code is written.
Taction Software is a mobile and web development company with US offices in Chicago, Cheyenne, Austin and Sacramento, plus a development center in Noida, India. It is on this list mainly because of one detailed telemedicine case study that reads like a full enterprise specification.
The client, according to its site, was a regional health system with 200+ providers across 15 specialties and no existing virtual care capability. Taction built HD video visits with a virtual waiting room, multi-participant sessions for family members or interpreters, screen sharing for lab and imaging review, and one calendar that blends virtual and in-person appointments. E-prescribing runs through Surescripts with EPCS support for controlled substances, and the Epic integration shows the chart inside the telemedicine interface and writes visit notes back to the encounter. The build also includes real-time eligibility checks, automated telehealth CPT coding, and a state-specific telehealth compliance rules engine.
The company reports 50,000+ virtual visits in year one, 94% patient satisfaction, an 8% virtual no-show rate against 23% in person, and $4.2M in telehealth billing. These are vendor-reported figures for an unnamed client, so ask for references.
Best for: health systems and large multi-specialty groups that need a full virtual care platform with prescribing, billing and EHR write-back rather than a standalone video app.
Arkenea is a US-based company that has built only healthcare software since 2011. It develops HIPAA-compliant web and mobile apps, custom EHRs and AI-powered healthcare tools, and lists telemedicine app development as a core service. The company says it has completed 150+ projects and frames compliance as an engineering choice: “HIPAA is an architectural decision, not a compliance checkbox.”
Its main published telehealth project is the Cumberland Health telehealth and patient engagement platform. The patient mobile app handles guided signup with one-time passcodes or Google and Apple sign-in, multi-language support, a required HIPAA consent step, and dependent profiles. Patients are matched with an available provider and move from chat into a live video consultation. Behind that sit separate Front Desk, Provider and Admin portals with provider availability windows to prevent over-booking, appointment status tracking, automatic closure of unattended appointments, in-record payment collection and an analytics dashboard.
Arkenea also says it was named Best Custom Healthcare Software Development Company at the GHP Global Excellence Awards for 2024, 2025 and 2026, and it publishes testimonials from healthcare clients including HomeHosp and ORLink.
Best for: practices and healthcare startups that want a vendor with no work outside healthcare and a clear model for front desk, provider and admin workflows around video visits.
Riseapps is a medical software company with offices in Lake Mary, Florida and Tallinn, Estonia, delivering healthcare software for clinics, startups and SaMD organizations since 2016. It targets telemedicine and virtual care providers directly, and its site shows ISO 27001 and ISO 9001 logos.
Its clearest telehealth case is Almond, a Los Angeles OB-GYN and functional medicine provider that wanted to test whether women would book and pay for ongoing virtual care without insurance-heavy workflows. Riseapps built HIPAA-compliant video visits and messaging, 24/7 self-serve booking for virtual and in-person visits, intake, clinician-built care plans, automated reminders and operational analytics. According to its site, Almond booked 462 new appointments in the first months after launch and went on to raise $7M to scale.
The company also builds on top of existing EHRs rather than replacing them. It lists a branded patient app for a multi-location practice built on athenahealth in eight weeks with no data migration, and a custom patient platform on eClinicalWorks for a women’s care clinic. Viemed, The Wound Pros, CareHalo and BrainMD are among the client logos it shows, and CareHalo appears as a remote patient monitoring case.
Best for: independent clinics and specialty practices that want a branded telehealth experience layered on the EHR they already use.
Orangesoft describes itself as a custom healthcare software development company founded in 2011. Its healthcare offerings include telemedicine app development, medical device software, IoMT and wearables, healthcare AI, clinical trial software and mental health apps, with integrations into EHRs, labs, imaging and medical devices. The site displays badges for ISO 9001:2015, HL7 FHIR, DICOM and EU MDR among others.
Its standout telehealth project is a post-stroke monitoring program set up by a US hospital network. Orangesoft built an FDA- and HIPAA-compliant web platform for medical staff with secure messaging and video and audio calls, plus a patient mobile app with telehealth visit reminders and video assessments for tracking recovery at home. The build includes two-factor authentication, encryption in transit and at rest, access controls and audit trails, and the company says it helped prepare documentation for the FDA submission process. According to its site, the program now supports more than 50,000 patients across the US.
It also lists a virtual hospital platform designed to deliver care without physical hospital infrastructure, which is relevant for hospital-at-home programs.
Best for: telehealth and remote care products that touch FDA regulation, such as software tied to rehabilitation, monitoring or medical devices.
Thinkitive is a healthcare technology company with US offices in Dover, Delaware and Edison, New Jersey. It says it serves 150+ healthcare customers, and its services cover custom healthcare software, EHR and EMR work, revenue cycle management, AI and interoperability. Its integration list is the relevant part for telehealth buyers: EHR integration, FHIR and SMART on FHIR capabilities, and labs and ePrescription integrations. The site footer lists SOC 2 Type II and ONC certified health IT.
Its published telehealth case study is a platform for a US provider of musculoskeletal physiotherapy to construction and manufacturing workers. Workers book virtual physiotherapy sessions, join video consultations through a patient portal with secure messaging and document sharing, and are tracked through wearable and remote monitoring integrations. The company reports physiotherapy bookings and attendance up 40%, appointment wait times down 50% and treatment adherence up 35%.
Client testimonials on its site also reference telehealth work, including Mesquite Valley Integrated Health on telemedicine consultations and UrCare Pros on an urgent care platform with integrated telehealth. A published case study for Kencore Health covers athenahealth EHR integration.
Best for: provider groups and health IT vendors whose telehealth features need to sit inside a broader EHR, billing and interoperability roadmap.
Itransition is a large software engineering company with offices in Decatur, Georgia and London, and it cites more than 25 years of software development experience. Its telemedicine practice covers real-time virtual consultations, group therapy, behavioral health management, chronic condition monitoring, emergency care and patient education, with specialty solutions for primary care, pediatrics, dermatology and neurology. It also offers Microsoft Cloud for Healthcare implementation alongside custom telemedicine software.
The case studies on its telemedicine page cover a wide range. A psychiatric telehealth solution reduced patient travel distance by 40%, according to the company. A remote patient monitoring suite for a US research center made case creation three times faster. Other projects include a telemedicine-ready EHR holding 28 years of data, a wellness platform with 100,000+ registered users, and a three-part remote asthma monitoring suite.
Itransition says it builds telehealth software to HIPAA, CCPA, GDPR, PIPEDA and NIST requirements and works with FHIR, ICD-10, CPT and DICOM. It also cites inclusion in Forrester’s 2022 Modern Application Development Services report.
Best for: enterprises and large provider networks that need a vendor with the headcount to run a multi-year telehealth program, especially on the Microsoft stack.
Innowise is headquartered in Warsaw, was founded in 2007, and says it has 3,500+ in-house IT professionals. It is a full-cycle software company rather than a healthcare specialist, but it publishes a detailed telemedicine app development case study that shows real depth.
The client was a telemedicine software provider with a web platform and white-label healthcare apps for the US market. Innowise built native iOS and Android apps that connect to the client’s EHR and EMR integrations, third-party apps and practice management software. The patient side includes multi-factor login, doctor search, a symptom chatbot, scheduling with push confirmations, video visits with in-call messaging and media sharing, recorded visits in HIPAA-compliant storage, vitals entry and medication tracking. The clinician side covers e-visits, prescribing, treatment plans and full patient records, while administrators handle billing and reimbursement.
The stack used Swift, Kotlin, Java 11 with Spring Boot, Kafka, Kurento for video, and AWS with Docker and Kubernetes. The company says the work has run from 2021 to the present, with pharmacy integrations planned, and estimates a 5 to 7% increase in economic outcomes for the client.
Best for: telehealth software vendors that already have a platform and need a large native mobile team to extend it.
Ask for two or three telehealth projects in production, with the features built, the stack, and a reference you can call. A firm with real telehealth app development experience will talk comfortably about video quality on weak connections, waiting room logic, no-show handling and what broke after launch. A firm without it will talk about “seamless experiences.”
Since there is no HIPAA certification for vendors, ask concrete questions instead. Will they sign a BAA? Which HIPAA-eligible cloud services and video SDKs will they use, and do those providers sign BAAs too? How are audit logs, role-based access, session timeouts and encryption at rest handled? Independent attestations such as SOC 2 Type II or ISO 27001 are useful signals of mature security practices, but they do not replace a HIPAA risk assessment of your own product.
EHR integration is usually the riskiest part of a telemedicine build. Ask whether the team has worked with your specific system (Epic, Oracle Cerner, athenahealth, eClinicalWorks, NextGen), whether it used FHIR APIs, SMART on FHIR launch or older HL7 v2 interfaces, and how long marketplace or app approval took. Writing visit notes back to the chart is harder than reading data out, so ask about write-back specifically.
If clinicians will prescribe inside your app, the vendor needs experience with an e-prescribing network such as Surescripts, usually through an intermediary like DoseSpot, and with EPCS requirements if controlled substances are involved. Ask how they handled identity proofing and two-factor authentication for prescribers on past projects, since these add weeks to a schedule.
A video visit app usually is not. A remote monitoring product that interprets device data, flags risk or guides treatment may be. If there is any chance your software falls under FDA or EU MDR rules, favor a firm with ISO 13485 processes and experience preparing regulatory documentation, and settle the regulatory question before development starts.
Get estimates that separate the MVP from later phases, and make sure integration, compliance work, QA and post-launch support are priced as line items. Vendor sales in this space are competitive, so do not let a polished pitch substitute for a written scope. Ask what is out of scope as clearly as what is in.
The best telemedicine app development firms on this list share one trait: they can point to telehealth products that real clinicians and patients use, with the video, prescribing, EHR and monitoring pieces documented on their own sites. Healthcare specialists like Topflight, Mindbowser and Arkenea suit startups and practices that want a focused partner, while ScienceSoft, Taction Software and Orangesoft bring depth in regulated or enterprise builds.
Larger engineering firms such as Itransition and Innowise make sense when the program needs scale or a big native mobile team, and teams weighing a cross-platform build can compare our list of Flutter development companies. Whichever direction you take, shortlist two or three firms, ask each to walk you through a live telehealth case study, and test their answers on HIPAA safeguards, EHR integration and e-prescribing before you sign.